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Anti-platelet Antibody Screening (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies that may be linked to a rare autoimmune condition affecting the kidneys, called primary membranous nephropathy. It involves a blood sample to detect specific proteins in your serum or plasma.

Quick summary

["This screening helps identify potential kidney-related autoimmune responses that may require further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57032-5
Short code
T palldm Ab Ser Ql IB
Synonyms
T palldm Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of antibodies targeting the platelet-associated phospholipase A₂ receptor (PLA2R), a protein often involved in kidney disease. These antibodies can be found in the blood and may indicate an immune system response that could damage kidney tissue.

Why It’s Done

Doctors may order this test if you have unexplained kidney problems, such as protein in urine, high blood pressure, or swelling, especially if you have no known kidney disease history. It can also be part of a broader evaluation for autoimmune kidney conditions.

What to Expect

A blood sample is taken from a vein, usually in your arm. The sample is then processed to detect specific antibodies. Results are qualitative (positive or negative) rather than a numeric value.

Preparation

No special preparation is needed for this test. You may eat and drink normally before your visit, but inform your healthcare provider about any medications you’re taking, as some may affect blood tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-PLA2R Antibody Screen

Frequently asked questions

This test helps determine if your symptoms could be related to an autoimmune condition like membranous nephropathy. Positive results suggest further testing (such as confirmation assays) may be needed to assess kidney function and guide treatment decisions.
What does a positive result mean?
A positive result indicates the presence of anti-PLA2R antibodies in your blood, which may suggest an autoimmune process affecting your kidneys. This does not confirm kidney disease alone but warrants additional evaluation by a healthcare provider to assess kidney function and next steps.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
No fasting is required for this test. However, always follow your healthcare provider’s instructions, as some tests may have specific guidelines.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy