Total Protein with Albumin and Globulin Separation (Serum)

Why This Test Matters

Protein is essential for many bodily functions, including maintaining healthy tissues, supporting immune function, and transporting nutrients. Your body produces two main types of protein in blood: albumin and globulins. Albumin helps keep fluids in your bloodstream, while globulins support immune responses and other functions. Abnormal levels can signal underlying health issues.

How the Test Works

A small blood sample is drawn and analyzed to measure total protein content. The sample is then separated to determine albumin and globulin levels, often using specialized laboratory techniques like electrophoresis or immunochemical methods.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if albumin is being measured separately. Wear a loose-fitting shirt for easy access to your arm.

Common Uses and Conditions

This test is often used to diagnose or monitor conditions such as liver disease (which can affect albumin production), kidney disease (which may alter protein balance), malnutrition, or certain immune disorders. It can also help track treatment progress for conditions like cirrhosis or protein-losing syndromes.