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Serum/plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, including albumin and other proteins like globulins.

Quick summary

["Total protein helps assess overall protein balance and potential kidney or liver issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47236-5
Short code
T palldm IgG+IgM SerPl Ql IA
Synonyms
T palldm IgG+IgM SerPl Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, or malnutrition. It can also help monitor protein loss due to conditions like kidney disease or certain cancers.

What Does a Result Mean?

Higher-than-normal results may suggest conditions like dehydration, multiple myeloma, or severe liver disease. Lower-than-normal results could indicate kidney disease, malnutrition, or liver problems.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. This test does not require fasting.

Common Conditions Monitored

This test is often used to monitor liver function, kidney health, and protein metabolism. It can also help diagnose or track conditions like cirrhosis, nephrotic syndrome, or protein-losing gastrointestinal diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Protein

Frequently asked questions

What Are My Results Likely To Be Asked About?
Your results may be compared to your baseline values from previous tests or to general reference ranges provided by your lab. If your results are outside the expected range, your doctor may ask for additional tests or further evaluation.
How Often Should I Get This Test?
The frequency depends on your health condition and treatment plan. Some people need this test monthly, quarterly, or annually, while others may only need it once or twice a year.
Can I Prepare for This Test?
No special preparation is needed for this blood test. However, always inform your healthcare provider about any medications or supplements you’re taking, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy