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Serum or plasma concentration of total protein (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins.

Quick summary

["Total protein helps assess your body’s protein balance and overall kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47238-1
Short code
T palldm IgG Ser Ql IA
Synonyms
T palldm IgG Ser Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to check for kidney disease, liver problems, dehydration, malnutrition, or other conditions that affect protein levels in the blood. It can also help monitor treatment responses in certain conditions.

What Does It Mean If Results Are Abnormal?

Low total protein levels might suggest kidney issues, liver disease, malnutrition, or severe dehydration. High levels could indicate dehydration, multiple myeloma, or other rare conditions like nephrotic syndrome.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then separated into serum (liquid after clotting) or plasma (liquid after anticoagulant use) for testing. This test does not require fasting.

Common Conditions Monitored

This test is often used to monitor kidney function, liver health, and protein synthesis. It may also be part of routine check-ups for patients with chronic illnesses like heart disease or diabetes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What does a ‘normal’ range mean for this test?
There is no single ‘normal’ range for total protein because it can vary based on age, sex, and overall health. Your doctor will compare your results to your own baseline or specific health needs.
How soon will I get my results, and what should I do next?
Results are typically available within a few days to a week, depending on your lab. Your doctor will discuss the meaning of your results and any next steps, such as further testing or lifestyle changes.
Can I eat or drink anything before this test?
No special preparation is needed for this test. You can eat and drink normally before your blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy