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Electrophoresis of Serum Proteins (Bromocresol Green)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood serum using a technique called electrophoresis. It helps identify abnormalities in protein levels that may indicate conditions like liver disease, kidney problems, or certain immune disorders.

Quick summary

["This test helps doctors assess protein balance in your blood, often used to detect underlying health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98224-9
Short code
T palldm IgM bands CSF IB
Synonyms
T palldm IgM bands CSF IB
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins into distinct bands based on their size and electrical charge. The test uses bromocresol green dye to identify specific protein groups, including albumin, globulins (such as alpha, beta, and gamma globulins), and other components. The results provide a visual profile of protein distribution.

Why It’s Done

Doctors may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or signs of organ dysfunction. It can also help diagnose conditions like multiple myeloma, liver disease, or chronic inflammation.

Sample Preparation and Testing Process

A blood sample is drawn, and the serum (liquid part after clotting) is separated and prepared for electrophoresis. The sample is placed in an electric field, causing proteins to migrate at different rates, creating visible bands. Bromocresol green dye binds to certain proteins, enhancing their visibility.

Common Conditions Evaluated

This test is particularly useful for identifying imbalances in albumin and globulin levels. Low albumin may suggest liver or kidney disease, while abnormal globulin patterns can indicate immune system disorders or chronic infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal results may signal underlying health issues, such as liver disease (reduced albumin), immune disorders (elevated gamma globulins), or kidney problems (altered protein fractions). Early detection can guide treatment decisions, including monitoring for conditions like cirrhosis, multiple myeloma, or autoimmune diseases.

Short name

Bromocresol Green Serum Protein Electrophoresis

Frequently asked questions

What Does a Normal Result Mean?
A normal result typically shows balanced protein distribution with distinct bands for albumin and globulins. However, individual results depend on your overall health, so doctors will interpret results in the context of your symptoms and medical history.
When Might I Need Follow-Up Testing?
If your results show unusual patterns, your doctor may recommend additional tests, such as liver or kidney function tests, to explore potential causes further. Follow-up may also include monitoring symptoms or adjusting treatments if needed.
How Long Does It Take to Get Results?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy