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Serum or plasma mass concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins. Proteins help maintain fluid balance, support immunity, and transport nutrients.

Quick summary

["Total protein levels can help identify conditions affecting blood composition or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47514-5
Short code
T palldm IgM CSF-aCnc
Synonyms
T palldm IgM CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like dehydration, kidney disease, liver problems, or certain infections. It can also help monitor long-term health in people with chronic illnesses.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours if your blood is drawn early in the morning. Wear a loose shirt for easy access to your arm.

What Happens During the Test?

A healthcare professional will insert a small needle into your arm to draw blood. You may feel a slight pinch, but it usually takes only a few seconds. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are typically reported in grams per deciliter (g/dL). While reference ranges vary by lab, lower than expected levels may suggest conditions like malnutrition or kidney issues, while higher levels could indicate dehydration, inflammation, or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What does a low total protein level mean?
A low total protein level may suggest conditions like malnutrition, kidney disease, or liver problems. It could also indicate excessive protein loss due to infections, inflammation, or certain medications. Your provider will review your symptoms and other test results to determine the cause.
What causes high total protein levels?
High total protein levels can result from dehydration, severe infections, inflammation, or conditions like multiple myeloma. Rarely, it may also be linked to certain medications or genetic factors. Your provider will investigate further if this is unexpected for you.
How often should I get this test?
The frequency depends on your health status. If you have a chronic condition like kidney disease or liver problems, your provider may recommend regular monitoring. Otherwise, this test is often done as needed for specific symptoms or diagnostic purposes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy