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C-reactive protein (CRP) with high-sensitivity measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when inflammation is present, often used to check for signs of infection or inflammation.

Quick summary

["hs-CRP helps track inflammation, a key marker for many health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69946-2
Short code
T palldm IgM CSF Ql IB
Synonyms
T palldm IgM CSF Ql IB
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor chronic conditions like heart disease, arthritis, or autoimmune disorders. It can also help detect infections or inflammation early, even when other symptoms aren’t present.

How Is the Sample Collected?

A small amount of blood is drawn from a vein, usually in your arm, using a needle. The blood is then sent to a lab for testing.

What Does a High or Low Result Mean?

Elevated levels may signal inflammation, infection, or conditions like rheumatoid arthritis or heart disease. Very low levels might suggest no active inflammation, but this isn’t always reliable alone. Always discuss results with your healthcare provider.

Common Conditions Monitored With This Test

hs-CRP is often used alongside other tests to assess risk for cardiovascular events, track inflammatory diseases, or evaluate responses to treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: hs-CRP is a marker for systemic inflammation, which can indicate underlying health risks. While not a definitive diagnosis, it supports broader clinical decisions, such as adjusting medications or planning preventive care.

Short name

hs-CRP

Frequently asked questions

What does a high hs-CRP level mean?
A high hs-CRP level suggests inflammation is present in your body, which could be due to infections, autoimmune diseases, or other health issues. Your doctor will consider this alongside other factors to determine the next steps.
How often should I get this test?
Your doctor will decide how often you need this test based on your health condition and medical history. Regular monitoring may be recommended for people with chronic diseases like heart disease or arthritis.
Can lifestyle changes affect hs-CRP levels?
Yes, lifestyle factors like diet, exercise, and stress management can influence inflammation. Small, healthy changes—such as eating a balanced diet, staying active, or managing stress—may help lower inflammation over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy