Immunoglobulin G (IgG) Subclass 2 (Serum)
This test measures the amount of Immunoglobulin G2 (IgG2), one of the types of antibodies your body produces to fight infections. IgG2 is important for protecting against certain bacteria and viruses.
["IgG2 helps your immune system defend against common pathogens and may influence how well your immune response works over time."]
Key facts at a glance
- LOINC
- 107002-8
- Short code
- T.pallidum Ab.IgG 15 Ser Ql IB
- Synonyms
- T.pallidum Ab.IgG 15 Ser Ql IB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does IgG2 Serve in Your Body?
IgG2 antibodies are part of your immune system’s defense against bacterial infections, particularly those that invade tissues. They play a role in neutralizing toxins and helping white blood cells clear infections. Levels can vary based on your immune health, past infections, and certain medical conditions.
Why Might Your Doctor Order This Test?
Your doctor may check IgG2 levels if you have recurrent infections, certain autoimmune diseases, or if you’re being treated for conditions like asthma, allergies, or immune deficiencies. It can also help assess how well your immune system is responding to treatments.
How Is This Test Performed?
A small blood sample is drawn from your arm, usually in a clinic or lab setting. The blood is processed to separate serum, where the IgG2 antibodies are measured using a specialized immunoassay technique. Results are compared to general reference ranges for healthy adults.
What Are Possible Results and What Do They Mean?
Results may indicate whether your IgG2 levels are lower or higher than typical. Low IgG2 could suggest a weakened immune response to certain infections, while higher levels might be seen in chronic immune activation or certain medical conditions. Always discuss results with your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IgG2 levels can be lower in people with certain immune disorders, such as common variable immunodeficiency (CVI) or other primary immunodeficiencies. They may also be affected by medications that suppress the immune system, such as corticosteroids. High IgG2 levels can sometimes be associated with chronic infections or autoimmune conditions, though this is less common.
Short name
IgG2 Level
Frequently asked questions
Why might my IgG2 levels be checked if I don’t have symptoms?
What does it mean if my IgG2 levels are low?
How often should I expect to have this test repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy