Skip to content

Immunoassay for Total Anti-IgG Antibodies (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of Immunoglobulin G (IgG), a type of antibody found in your blood. IgG is important for long-term immunity and helps protect against infections.

Quick summary

["IgG antibodies help your body fight infections and provide long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107006-9
Short code
T.pallidum Ab.IgG band 44 Ser Ql IB
Synonyms
T.pallidum Ab.IgG band 44 Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG antibodies are a key part of your immune system. They help your body recognize and fight foreign substances like bacteria and viruses. This test checks the overall level of IgG in your blood, which can be important for diagnosing or monitoring conditions related to immune function.

Why Might You Need This Test?

Doctors may order this test if you have symptoms of a weakened immune system, such as frequent infections, unusual bruising, or prolonged healing of wounds. It can also be used to monitor immune responses before or after treatments like chemotherapy or immune-modulating therapies.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the serum, which is tested for IgG antibodies using an immunoassay method. This method detects the presence and amount of IgG antibodies in your blood.

What Are Possible Results?

Results can vary based on your health and medical history. While specific reference ranges may differ by lab, lower than expected levels might suggest immune deficiencies, while higher levels could be seen in chronic infections, autoimmune diseases, or certain immune responses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total IgG Antibody Test

Frequently asked questions

What does a low IgG level mean?
A low IgG level may suggest an immune system that isn’t producing enough antibodies to fight infections effectively. This can be linked to conditions like CVID or other immune deficiencies. Your doctor may recommend additional tests or treatments to support your immune function.
What does a high IgG level mean?
High IgG levels can occur due to chronic infections, autoimmune diseases, or as a response to vaccines or certain medications. It’s important to discuss these findings with your healthcare provider to understand the underlying cause and any necessary next steps.
Can IgG levels change over time?
Yes, IgG levels can fluctuate based on your health, immune response, and treatments. Regular monitoring may be needed if you have a condition that affects your immune system, such as chronic illnesses or ongoing immune therapy.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy