Total Protein with Albumin-to-Globulin Ratio (Serum/Plasma)
This test measures your total protein levels in your blood and evaluates the balance between albumin and globulin proteins, which can help assess overall protein status and potential immune or liver function issues.
["Understanding your protein balance may help identify conditions like malnutrition, liver disease, or immune disorders."]
Key facts at a glance
- LOINC
- 98213-2
- Short code
- T pall IgG + IgM + bands Pnl Ser IB
- Synonyms
- T pall IgG + IgM + bands Pnl Ser IB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Measured?
Total protein is the sum of all proteins in your blood, including albumin and globulin. Albumin is a key protein that helps maintain fluid balance in your body, while globulins are involved in immune function and transport of substances like hormones and metals. This test provides a ratio to compare these two protein types.
Why It Matters in Your Health?
Abnormal protein levels or ratios can signal underlying health concerns. Low total protein or low albumin might indicate malnutrition, liver disease, or kidney problems, while high globulin levels could suggest chronic inflammation or immune system activity.
Sample Preparation and Testing Process
A blood sample is drawn from a vein, typically in the arm. The sample is processed to separate serum or plasma, where protein levels are measured using a specialized laboratory technique. This test is usually done as part of a routine blood panel.
Common Conditions This Test Helps Diagnose
This test can help diagnose or monitor conditions such as liver disease (e.g., cirrhosis), kidney disease, malnutrition, chronic infections, or autoimmune disorders. It may also be used to assess protein-losing conditions like gastrointestinal bleeding or proteinuria.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein & Albumin-Globulin Ratio
Frequently asked questions
What does a low or high total protein level mean?
How often should I get this test?
Can diet or lifestyle changes affect protein levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy