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Urine Microalbumin-to-Creatinine Ratio (Microalbumin-to-Creatinine Ratio)

Published: August 9, 2026Updated: August 16, 2026

This test measures small amounts of a protein called albumin in your urine, compared to a measure of your kidney function (creatinine). It helps check for early kidney damage.

Quick summary

["A useful early indicator of kidney problems, often checked in people at higher risk of diabetes or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8249-5
Short code
Trans Cells UrnS Ql Micro
Synonyms
Trans Cells UrnS Ql Micro
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters for Kidney Health

Albumin is normally filtered out of your blood by your kidneys and excreted in urine. If your kidneys are damaged, they may not work as well, allowing more albumin to leak into urine. This test helps detect early kidney issues by measuring tiny amounts of albumin in relation to creatinine, which reflects kidney function. Early detection can help manage conditions like diabetes or high blood pressure before they cause serious damage.

What to Expect Before the Test

No special preparation is needed for this urine test. You may collect a midstream urine sample in a clean container, or your healthcare provider may use a catheter or other method to collect a sample. Drink plenty of water the day before if you’re asked to, but avoid excessive exercise or strenuous activity that could affect urine composition.

How the Test Works

The test compares the amount of albumin (a protein) to creatinine (a waste product from muscle breakdown) in your urine. Creatinine levels are used as a reference to ensure the albumin measurement is accurate, even if urine volume varies. This ratio helps identify kidney problems early, often before symptoms appear.

When Your Doctor Might Order This Test

Your doctor may recommend this test if you have diabetes, high blood pressure, a family history of kidney disease, or other risk factors for kidney problems. It’s also used to monitor kidney function in people with chronic conditions or after treatments that could affect kidneys.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Microalbumin-to-Creatinine Ratio

Frequently asked questions

What does a high or low result mean?
A high ratio may indicate early kidney damage, especially in people with diabetes or high blood pressure. A low ratio usually means no significant kidney issues, but your doctor will consider your overall health and other test results.
Do I need to fast before this test?
No fasting is required. However, your doctor may ask you to avoid certain foods or medications that could affect urine composition, such as large amounts of salt or certain supplements. Always follow your provider’s specific instructions.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition. For example, people with diabetes may get it checked yearly, while others with risk factors might need it more frequently.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy