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: Transferrin

Published: August 9, 2026Updated: August 17, 2026

: Transferrin is a protein made mainly by your liver that carries iron through your bloodstream to where your body needs it. A transferrin test measures how much of this iron-transport protein is in your blood.

Quick summary

[": Transferrin testing helps show whether your body has enough iron-carrying capacity or is responding to iron deficiency, iron overload, or other conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
111486-7
Short code
Transferring
Synonyms
Transferring
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
350
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84466
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Transferrin?

: Transferrin is a protein that binds iron and transports it in the blood. It is produced primarily by the liver, and measuring its level gives information about your body's iron status and how well it can move iron to tissues such as bone marrow.

: Why the Test Is Done

: Your healthcare provider may order a transferrin test as part of an iron panel to evaluate anemia, suspected iron deficiency, iron overload, or chronic illness. It can also be used to monitor liver function or nutritional status in certain situations.

: How the Test Is Performed

: The test usually requires a blood sample drawn from a vein in your arm. In most cases no special preparation is needed, but your provider may ask you to fast or to avoid iron supplements before the draw if other iron tests are being run at the same time.

: What the Results Can Mean

: Transferrin levels can be low, normal, or high. Low levels may occur with liver disease, inflammation, malnutrition, or iron overload, while high levels may occur with iron deficiency or during pregnancy. Results are interpreted together with other iron tests rather than on their own.

Reference range

NCBI: Transferrin 200-350 mg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Transferrin is part of the iron panel used to assess iron status. Changes in transferrin can help distinguish iron deficiency from anemia of chronic disease and can support evaluation of iron overload or liver and nutritional disorders. Because results depend on context, they should be interpreted by a clinician alongside symptoms, other iron tests, and medical history.

Short name

: NONE

Frequently asked questions

: Do I need to fast before a transferrin test?
: Not usually. Fasting is generally not required for transferrin alone, but if your provider is ordering a full iron panel, follow any specific instructions you are given.
: Can medicines or supplements affect transferrin results?
: Yes. Iron supplements, some medications, pregnancy, and inflammatory conditions can affect transferrin levels. Tell your provider about all medicines, supplements, and recent illnesses before testing.
: Does an abnormal transferrin result mean I have a disease?
: Not necessarily. Transferrin results must be interpreted with other iron tests and your clinical picture. Your provider will explain what your results mean and whether further testing is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy