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Serum Transferrin Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of transferrin, a protein in your blood that helps carry iron. Low levels may indicate conditions like anemia or liver disease.

Quick summary

["Transferrin helps carry iron in your blood and can signal potential health concerns if levels are too high or too low."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
110293-8
Short code
Transferrin Msmt SerPl
Synonyms
Transferrin Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
350
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84466
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test to check for iron metabolism issues, such as iron deficiency or overabsorption. It can also help diagnose or monitor conditions like liver disease, kidney disease, or certain types of anemia. Sometimes, it’s used to evaluate nutritional status or response to treatment.

What Does a Transferrin Test Tell Us?

Transferrin levels can give clues about how well your body is using iron. Low levels might suggest iron deficiency or malabsorption problems, while very high levels could indicate conditions like liver disease or certain cancers. However, results alone don’t diagnose a condition—they’re part of a bigger picture.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab to measure transferrin levels using a specialized test method. You may feel a small pinch when the needle is inserted, but the process is quick and usually painless.

What Do My Results Mean?

Your results will be compared to a reference range provided by your lab. While reference ranges can vary slightly by lab, they help determine if your transferrin level is within normal limits, low, or high. Your healthcare provider will discuss these results with you and explain what they mean for your health.

Reference range

NCBI: Transferrin 200-350 mg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance of Transferrin Levels

Short name

Transferrin Level

Frequently asked questions

How often will I need this test?
The frequency of this test depends on your health condition and why it was ordered. Some people may need it once, while others may have it checked regularly, especially if they have ongoing health issues like liver disease or anemia. Your doctor will let you know how often to expect results.
What are the normal ranges for transferrin?
There isn’t a single standard range for transferrin levels because they can vary based on factors like age, sex, and overall health. Your lab will provide your specific reference range, and your doctor will interpret these results in the context of your medical history.
Can I eat or drink anything before this test?
You can typically eat and drink normally before this blood test unless your doctor gives specific instructions. Most tests don’t require fasting, but it’s always best to follow your healthcare provider’s advice to avoid any unnecessary stress or complications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy