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Serum Transferrin Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of transferrin, a protein in your blood that helps carry iron to your body’s tissues.

Quick summary

["Transferrin helps regulate iron levels and supports healthy red blood cell production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
3034-6
Short code
Transferrin SerPl-mCnc
Synonyms
Transferrin SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
350
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84466
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Transferrin?

Transferrin is a key protein in your blood that binds iron and transports it to cells that need it, such as those involved in making red blood cells. It plays a critical role in preventing iron buildup, which can be harmful if too much iron accumulates in your body.

Why Might You Need This Test?

Your doctor may order this test if they suspect conditions like iron deficiency anemia, iron overload (hemochromatosis), or certain liver or kidney disorders. It can also be part of a broader evaluation for nutritional deficiencies or metabolic issues.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where transferrin levels are measured using a specialized analytical method. Results are reported as a mass concentration in the blood.

What Do the Results Mean?

Results are compared to reference ranges provided by your lab. Low transferrin levels may indicate iron deficiency or liver/kidney problems, while very high levels could suggest conditions like inflammation or certain genetic disorders.

Reference range

NCBI: Transferrin 200-350 mg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Transferrin Level

Frequently asked questions

How often do I need this test?
This test is typically ordered as part of a routine blood panel or when symptoms or test results suggest a need for iron or protein evaluation. Frequency depends on your health status, symptoms, and doctor’s recommendations.
What are the normal reference ranges?
Reference ranges vary by lab, but transferrin levels generally fall between approximately 200 to 400 mg/dL. Your doctor will interpret results in the context of your overall health and medical history.
Can I prepare for this test?
No special preparation is needed, but avoid heavy meals or caffeine before your blood draw to ensure accurate results. Follow any specific instructions your doctor provides.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy