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Transferrin mass concentration (serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of transferrin, a protein in your blood that helps carry iron. Low levels may indicate conditions like iron deficiency or liver disease.

Quick summary

["Transferrin helps your body use iron efficiently, and its levels can signal potential health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
3035-3
Short code
Transferrin Ur-mCnc
Synonyms
Transferrin Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
200
Ref high
350
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84466
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order this test if they suspect conditions like iron deficiency anemia, liver disease, or certain types of malnutrition. It can also help monitor treatment progress for these conditions.

What Does a Transferrin Test Involve?

A small blood sample is taken from a vein in your arm. The blood is then sent to a lab where it is analyzed to measure the transferrin protein concentration.

What Are Common Results and Their Meanings?

While specific reference ranges vary by lab, lower than expected transferrin levels might suggest iron deficiency or liver problems, while higher levels could be linked to certain inflammatory conditions or pregnancy.

How Is This Test Different from Other Blood Tests?

Unlike tests that measure iron directly (such as ferritin or total iron-binding capacity), this test focuses specifically on the transferrin protein itself, which helps transport iron in your bloodstream.

Reference range

NCBI: Transferrin 200-350 mg/dLN/A

Specimen: urine

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Transferrin levels can be useful in diagnosing or monitoring conditions like iron deficiency anemia, where transferrin may be elevated due to the body’s attempt to bind more iron. In liver disease, transferrin levels might be lower because the liver’s function is impaired. Additionally, chronic inflammation or certain infections can sometimes affect transferrin production.

Short name

Transferrin Level

Frequently asked questions

What does a low transferrin level mean?
A low transferrin level may indicate conditions such as liver disease, iron deficiency, or malnutrition. Your doctor will consider your overall health and other test results to interpret these findings.
How often should I get this test?
The frequency of this test depends on your medical needs. Your doctor will determine how often to check your transferrin levels based on your symptoms, diagnosis, or treatment plan.
Can diet affect transferrin levels?
Yes, diet can influence transferrin levels. Eating foods rich in iron or certain vitamins (like vitamin C) may affect iron transport, indirectly impacting transferrin. However, dietary changes alone won’t replace a medical evaluation of your results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy