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Serum Immunoglobulin (Ig) Profile with Allergen-Specific Testing (Screening Mix)

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to common allergens, including common airborne allergens, foods, and environmental triggers. It helps identify whether your immune system is reacting to specific substances.

Quick summary

["This screening helps determine if allergens may be causing your symptoms and guides allergy treatment options."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71371-9
Short code
Tree Allerg Mix 9 IgE Qn
Synonyms
Tree Allerg Mix 9 IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test includes measurements of total serum immunoglobulin levels (IgE, IgG, IgA, IgM) and specific IgE antibodies against a mix of common allergens. IgE is particularly important because it’s linked to allergic reactions. The mix typically includes allergens like pollen, dust mites, pet dander, mold, certain foods, and insect venom.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms like sneezing, itching, rash, hives, swelling, difficulty breathing, or digestive issues that suggest an allergic reaction. It’s also used to evaluate suspected food allergies, environmental allergies, or reactions to insect stings.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it’s analyzed using immunoassay methods to detect specific IgE antibodies against the allergens in the mix. Results are reported as positive or negative for each allergen, indicating whether your immune system is sensitized to them.

What Do My Results Mean?

Positive results for specific allergens mean your immune system has detected those substances and may produce symptoms when exposed. However, a positive test alone doesn’t confirm an allergy—it only indicates sensitization. Further evaluation, such as skin prick tests or additional blood tests, may be needed to confirm an allergy and guide treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test helps identify potential allergens driving symptoms, allowing for targeted allergy avoidance, immunotherapy (like allergy shots), or other treatments. It’s particularly useful for diagnosing conditions like hay fever, food allergies, or allergic asthma. However, results should always be interpreted by a healthcare provider in the context of your symptoms and medical history.

Short name

Ig Allergy Screen (Serum)

Frequently asked questions

What does a positive result mean?
A positive result for an allergen means your immune system has detected that substance and may react to it. This doesn’t mean you’ll always have symptoms, but it suggests you could be sensitized. Your doctor will discuss next steps, such as avoiding the allergen or further testing.
Can false positives or negatives happen?
Yes, both false positives and false negatives can occur. False positives may happen if you’ve recently been exposed to the allergen or have another condition affecting your immune response. False negatives are less common but can occur if the test isn’t sensitive enough or if you haven’t been exposed recently. Your doctor will help interpret results in the right clinical context.
How often should I get this test?
This test is typically done once as part of an allergy evaluation. If you have ongoing symptoms or need to monitor allergies, your doctor may recommend retesting after a period of allergen avoidance or if symptoms change.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy