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Trichothecene (e.g., Deoxynivalenol) in Serum/Plasma by High-Performance Liquid Chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific mycotoxin compounds, such as deoxynivalenol (DON), found in certain fungi that can contaminate food and feed. These toxins may affect your health if present in high amounts.

Quick summary

["Detecting certain mycotoxins in your blood may help identify exposure risks or potential health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49593-7
Short code
Trichothecene IgA Ser IA-aCnc
Synonyms
Trichothecene IgA Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you’ve been exposed to contaminated food, have symptoms like nausea, vomiting, or gastrointestinal distress, or if you’re at higher risk for mycotoxin-related illnesses (e.g., due to occupational or environmental exposure).

What Does the Test Measure?

The test detects levels of trichothecene mycotoxins, such as deoxynivalenol (DON), in your blood. These toxins are produced by certain molds and can be harmful if ingested or inhaled in large quantities.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The sample is processed to separate serum or plasma, which is then analyzed using a specialized laboratory method to measure trichothecene levels.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to avoid certain medications or foods that could interfere with results. Always follow your healthcare provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Mycotoxins and Health Risks

Short name

Trichothecene Toxin Screening

Frequently asked questions

Mycotoxins like trichothecenes can cause acute poisoning (e.g., vomiting, diarrhea) or chronic health effects, including immune suppression or long-term organ damage. While blood levels may not always correlate with exposure, this test helps assess potential risks in certain high-risk scenarios.
How accurate is this test for detecting trichothecene exposure?
This test measures trichothecene levels in your blood, which can indicate recent exposure. However, results may not always reflect past or long-term exposure, as mycotoxins can be metabolized or cleared from the body over time.
Can I eat certain foods before this test?
No specific dietary restrictions are required, but if you suspect recent exposure to contaminated food, inform your healthcare provider before testing.
If results are elevated, your provider may discuss further testing, lifestyle adjustments, or medical evaluation based on your symptoms and exposure history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy