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Triglyceride in Lipoprotein Subfractions (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of triglycerides in different types of high-density lipoprotein (HDL) particles in your blood, which helps assess lipid metabolism and cardiovascular risk.

Quick summary

["Understanding HDL triglyceride levels can help identify potential heart health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53528-6
Short code
Trigl in HDL3 SerPl-sCnc
Synonyms
Trigl in HDL3 SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
40
Ref high
60
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
83700
SNOMED
113079008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have risk factors for heart disease, such as high cholesterol, a family history of heart problems, or if you’re experiencing symptoms like chest pain or fatigue. It may also be used to monitor treatment for conditions affecting lipid metabolism.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw to ensure accurate results. Wear a loose-fitting shirt for easy access to your arm.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick and typically painless. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results provide detailed breakdowns of triglycerides within specific HDL subfractions, helping doctors evaluate how lipids are distributed in your bloodstream and whether they may contribute to cardiovascular risks.

Reference range

Adult males: >40 mg/dL; Females: >50 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Triglyceride Profile (HDL Subfractions)

Frequently asked questions

What does a high triglyceride level in HDL subfractions mean?
High levels in certain HDL subfractions may suggest imbalances in lipid metabolism that could increase cardiovascular risk. Your doctor will interpret results in the context of your overall health and may recommend further testing or adjustments to your care plan.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you once they are ready for discussion.
Can diet or exercise affect this test?
Yes, lifestyle factors like diet, exercise, and weight management can influence triglyceride levels. If you’re undergoing treatment, follow your doctor’s advice on dietary restrictions (e.g., fasting) to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy