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Urinary Creatinine-to-Creatinine Clearance Ratio (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products by comparing creatinine levels in your urine over 24 hours. It helps assess kidney function and blood flow to the kidneys.

Quick summary

["This test helps doctors evaluate kidney health and blood flow by tracking waste removal over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99901-1
Short code
Tri-Phos Cry #/area UrnS Comp Assist
Synonyms
Tri-Phos Cry #/area UrnS Comp Assist
Category
electrolyte
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
computer-assisted
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect kidney disease, poor kidney function, or conditions affecting blood flow to the kidneys. It can also be used to monitor chronic kidney conditions or after treatments that might impact kidney function.

How the Test Works

You’ll collect all urine for 24 hours in a special container. The test measures creatinine, a waste product naturally present in your blood and urine, to estimate how well your kidneys filter it out.

Sample Collection

You’ll start collecting urine immediately after waking up, emptying your bladder into the container, and continue until you collect urine for the next 24 hours. Discard the first morning urine to avoid contamination. Store the urine in a cool place and return it to your doctor’s office or lab on time.

What to Expect

No special preparation is needed, but avoid strenuous activity or certain medications that could affect kidney function before testing. Follow your doctor’s instructions carefully.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low results may indicate kidney disease, poor blood flow, or dehydration. High results could suggest kidney damage, obstruction, or conditions like polycystic kidney disease. This test helps diagnose and monitor kidney function and related conditions.

Short name

24-Hour Urine Creatinine Clearance

Frequently asked questions

What causes false low results?
False low results may occur if you didn’t collect urine for the full 24 hours, had dehydration, or took certain medications that affect kidney function. Make sure to follow all collection instructions precisely.
What causes false high results?
False high results can happen if the urine sample was contaminated, improperly stored, or if you had muscle breakdown (e.g., from injury or exercise) before testing. Ensure your urine is fresh and properly collected.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition. It may be done yearly or more frequently if you have chronic kidney disease or other related conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy