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Thyroid-stimulating hormone (TSH) with serum/plasma measurement by immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH is a hormone produced by your pituitary gland that helps regulate your thyroid function.

Quick summary

["TSH helps your thyroid produce hormones that control metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47948-5
Short code
TSH 15M p LRH IV SerPl-aCnc
Synonyms
TSH 15M p LRH IV SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for thyroid problems, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). It can also be used to monitor thyroid function during treatment for thyroid disorders or after thyroid surgery.

What Does a TSH Test Measure?

TSH levels help determine whether your thyroid is working too slowly or too quickly. High TSH levels often suggest hypothyroidism, while low TSH levels may indicate hyperthyroidism or other conditions affecting the pituitary or thyroid.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is analyzed to measure TSH levels using an immunoassay method.

What Are Common Results and Their Meanings?

Results can vary based on individual health, age, and other factors. High TSH levels may signal hypothyroidism, while very low levels may suggest hyperthyroidism or conditions like pituitary tumors. Your results will be interpreted by your healthcare provider in the context of your overall health.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: TSH plays a critical role in thyroid hormone regulation. Abnormal TSH levels can indicate underlying thyroid dysfunction, which may require further evaluation or treatment to manage symptoms like fatigue, weight changes, or mood issues.

Short name

TSH (Serum/Plasma)

Frequently asked questions

What causes abnormal TSH levels?
Abnormal TSH levels can result from thyroid disorders (such as Hashimoto’s disease or Graves’ disease), pituitary gland issues, or other medical conditions affecting hormone balance. Lifestyle factors like stress, certain medications, or iodine deficiency may also influence results.
How long does it take to get results?
Results from a TSH test are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can diet or supplements affect TSH test results?
Yes, certain foods (like soy products or excessive iodine) and supplements (such as selenium or multivitamins) may temporarily affect thyroid function and TSH levels. Avoiding these for a few days before testing can help ensure more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy