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Thyroid Stimulating Hormone (TSH) with 15-Minute Post-Random Serum Measurement for Thyroid Function Assessment

Published: August 9, 2026Updated: August 16, 2026

This test measures your thyroid-stimulating hormone (TSH) level after a short period of fasting to help evaluate thyroid function and rule out conditions like hypothyroidism or hyperthyroidism.

Quick summary

["A TSH test helps your doctor check if your thyroid is working properly, often after fasting for 15 minutes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58834-3
Short code
TSH 15M pre chal SerPl-aCnc
Synonyms
TSH 15M pre chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like fatigue, weight changes, or unexplained issues with metabolism. It can also be part of routine thyroid screening or monitoring for conditions like hypothyroidism or hyperthyroidism. The 15-minute post-random measurement helps assess how quickly your body responds to thyroid hormone levels after a short fast.

What to Expect Before the Test

You’ll typically fast for about 15 minutes before the blood draw. Avoid eating or drinking anything except water during this time. Your blood will be taken from a vein, usually in your arm, and sent to the lab for testing.

What the Test Results Mean

TSH levels can vary based on your overall health, age, and medications. High levels may suggest hypothyroidism (underactive thyroid), while low levels could indicate hyperthyroidism (overactive thyroid) or other issues. Your doctor will interpret the results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test is primarily used to diagnose or monitor thyroid disorders, including primary hypothyroidism, secondary hypothyroidism, and sometimes hyperthyroidism. It can also help assess thyroid function in people with symptoms like weight gain, depression, or fatigue.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Management

Short name

TSH Post-Random Check

Frequently asked questions

What does a high TSH level mean?
A high TSH level often indicates hypothyroidism, meaning your thyroid isn’t producing enough hormones. This can lead to symptoms like fatigue, cold intolerance, or weight gain. Your doctor may recommend treatment, such as thyroid hormone replacement, to restore balance.
What does a low TSH level mean?
A low TSH level may suggest hyperthyroidism or an overactive thyroid, though other conditions can cause low TSH as well. Symptoms might include weight loss, anxiety, or rapid heartbeat. Further testing may be needed to determine the exact cause.
Why might my doctor order this test?
Your doctor might order this test if you have symptoms of thyroid issues, are being evaluated for thyroid disease, or if you have a family history of thyroid disorders. It can also be part of routine check-ups or monitoring for conditions like Hashimoto’s disease or Graves’ disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy