Thyroid Stimulating Hormone (TSH) with Serum/Plasma Measurement
This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH helps regulate your thyroid gland’s activity, which affects metabolism, energy levels, and overall health.
["TSH helps doctors check if your thyroid is working properly and adjusts to hormone imbalances."]
Key facts at a glance
- LOINC
- 50541-2
- Short code
- TSH 20M p TRH SerPl-aCnc
- Synonyms
- TSH 20M p TRH SerPl-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.4
- Ref high
- 4
- Critical range
- 0.1 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order a TSH test to diagnose or monitor thyroid disorders, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). It’s often the first test for thyroid issues because it’s sensitive and easy to perform. TSH levels can also be checked during pregnancy, before starting certain medications, or if you have symptoms like fatigue, weight changes, or unexplained mood swings.
What to Expect Before the Test
No special preparation is usually needed, but your doctor might ask you to avoid certain medications (like thyroid hormone replacements) for a few days before testing. If you’re pregnant or breastfeeding, let your healthcare provider know. You’ll typically have a small needle inserted into your arm or a blood sample drawn from your hand or finger.
What the Results Mean
TSH results help determine whether your thyroid is producing too much or too little hormone. High TSH levels often indicate hypothyroidism, while very low levels may suggest hyperthyroidism. Your doctor will compare your results to your symptoms and other tests to make a diagnosis.
Common Symptoms to Watch For
If your TSH levels are abnormal, you might experience symptoms like unexplained fatigue, weight changes (gain or loss), dry skin, hair loss, or depression. Always discuss any symptoms with your doctor, as thyroid issues can affect many parts of your body.
Reference range
Adult: 0.4-4.0 mIU/LN/A
Take your thyroid medication after the blood draw if applicable. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
TSH Level
Frequently asked questions
What does a high TSH level mean?
A low TSH level may indicate an overactive thyroid (hyperthyroidism) or a condition called thyroiditis. Symptoms could include weight loss, anxiety, rapid heartbeat, or tremors. Your doctor will likely order additional tests to confirm the cause and guide treatment.
Diet alone rarely affects TSH levels, but certain foods or supplements (like soy, selenium, or iodine) may interact with thyroid function. Avoiding large amounts of these for a few days before testing can help ensure accurate results. Always follow your doctor’s instructions.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy