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Thyroid Stimulating Hormone (TSH) with Serum/Plasma Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood, which helps your thyroid gland produce hormones that regulate metabolism.

Quick summary

["TSH helps diagnose and monitor thyroid conditions like hypothyroidism or hyperthyroidism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47952-7
Short code
TSH 30M p LRH IV SerPl-aCnc
Synonyms
TSH 30M p LRH IV SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check for thyroid problems, such as whether your thyroid is working too slowly (hypothyroidism) or too quickly (hyperthyroidism). It’s often used as part of routine check-ups, especially in older adults or those with symptoms like fatigue, weight changes, or mood swings.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your lab uses a specific method, but this is rare for standard TSH testing. Bring any medications you’re taking, as some (like certain thyroid medications) can affect results.

What the Test Results Mean

TSH results help determine whether your thyroid is functioning normally. Low TSH may suggest hyperthyroidism, while high TSH often points to hypothyroidism. Your provider will interpret results in relation to your symptoms and medical history.

Common Conditions Linked to TSH Abnormalities

High TSH levels can indicate conditions like Hashimoto’s thyroiditis (an autoimmune disease) or primary hypothyroidism. Low TSH may signal hyperthyroidism, Graves’ disease, or pituitary issues. Always discuss results with your doctor.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

TSH abnormalities can cause fatigue, weight changes, depression, or other symptoms. Regular monitoring helps manage thyroid disorders and prevent complications like heart problems or bone loss.

Short name

TSH Level

Frequently asked questions

What causes TSH levels to be too high or too low?
High TSH is often due to underactive thyroid (hypothyroidism), but it can also result from pituitary disorders, thyroid surgery, or certain medications. Low TSH may signal overactive thyroid (hyperthyroidism), thyroid nodules, or pituitary tumors. Symptoms vary widely and may include unexplained weight changes or mood swings.
Can diet or lifestyle affect TSH test results?
Dietary supplements (like soy or selenium) or certain medications (e.g., lithium, amiodarone) can influence thyroid function and may affect TSH levels. Avoiding these temporarily may help clarify results. Always inform your provider about all medications or supplements you take.
How often should I get a TSH test?
Your provider will determine frequency based on your health status. Typically, TSH is checked annually for stable thyroid conditions or more often if symptoms change. Follow-up tests may be needed if you experience new symptoms or have risk factors like family history of thyroid disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy