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Thyroid Stimulating Hormone (TSH) with Serum/Plasma Measurement by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This blood test measures your thyroid-stimulating hormone, a key hormone that helps regulate your metabolism and thyroid function.

Quick summary

["Your TSH level helps doctors check for thyroid problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12940-3
Short code
TSH 30M pre chal SerPl-aCnc
Synonyms
TSH 30M pre chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a TSH test to diagnose or monitor conditions like hypothyroidism (underactive thyroid), hyperthyroidism (overactive thyroid), or thyroid cancer. It’s also used to check for pituitary gland issues that affect thyroid hormone production.

What to Expect Before the Test

No special preparation is needed, but avoid smoking or caffeine 30 minutes before the blood draw. If you’re on thyroid medication, check with your doctor first—some medications can affect TSH levels.

What the Results Mean

Higher-than-normal TSH often suggests hypothyroidism, while very low TSH may indicate hyperthyroidism or thyroid dysfunction. Your doctor will interpret results in relation to your symptoms and medical history.

Common Conditions This Test Helps Identify

This test is critical for diagnosing thyroid disorders, including Hashimoto’s disease (autoimmune hypothyroidism), Graves’ disease (hyperthyroidism), and thyroid nodules. It can also help assess pituitary dysfunction or thyroid hormone resistance.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

TSH levels can be influenced by stress, pregnancy, certain medications (e.g., lithium, amiodarone), and chronic illnesses like kidney disease or liver failure. Always discuss any recent changes in your health or medications with your provider.

Short name

TSH Level

Frequently asked questions

Why might my TSH test show unexpected results even if I feel fine?
Unexpected results could be due to recent stress, medication use, or underlying conditions like thyroiditis (temporary inflammation). Your doctor may repeat the test or check additional thyroid hormone levels (like free T4) for clarity.
Can diet affect my TSH test results?
Dietary changes, such as excessive iodine intake (e.g., from seafood or supplements) or severe calorie restriction, can temporarily alter TSH levels. Avoid extreme diets or supplements before testing unless advised by your doctor.
What if my TSH is borderline? What should I do next?
A borderline TSH result may require further testing, such as free T4 or thyroid antibodies (e.g., TPO antibodies). Your doctor will guide you on next steps, which could include retesting or additional evaluations to rule out conditions like subclinical hypothyroidism or autoimmune thyroid disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy