Thyroid Stimulating Hormone (TSH) with Serum/plasma Measurement
This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH helps regulate your thyroid gland’s activity, which is crucial for metabolism, energy levels, and overall health.
["TSH helps your doctor assess thyroid function and identify potential thyroid disorders."]
Key facts at a glance
- LOINC
- 33258-5
- Short code
- TSH 30M p TRH SerPl-aCnc
- Synonyms
- TSH 30M p TRH SerPl-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.4
- Ref high
- 4
- Critical range
- 0.1 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order a TSH test to check for thyroid problems, such as hypothyroidism (when your thyroid isn’t producing enough hormones) or hyperthyroidism (when it produces too much). It’s often the first test recommended when symptoms like fatigue, weight changes, or unexplained mood swings are present.
How the Test Works
A small blood sample is taken from a vein in your arm. The sample is sent to a lab, where it’s analyzed to measure TSH levels using an immunoassay method. This test helps determine whether your thyroid is functioning normally or if further evaluation is needed.
What to Expect Before the Test
No special preparation is usually required, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic or hormonal evaluation. Let your doctor know about any medications you’re taking, as some can affect TSH results.
What the Results Mean
Results are interpreted based on your symptoms and overall health. High TSH levels often suggest hypothyroidism, while very low levels may indicate hyperthyroidism. Your doctor will discuss the results with you and may recommend additional tests if needed.
Reference range
Adult: 0.4-4.0 mIU/LN/A
Take your thyroid medication after the blood draw if applicable. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
TSH Level
Frequently asked questions
What does a TSH test help detect?
Can TSH levels change over time?
Is fasting required for a TSH test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy