Skip to content

Thyroid-stimulating hormone (TSH) with serum/plasma concentration measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH is a hormone produced by your pituitary gland that regulates thyroid function.

Quick summary

["TSH helps your body maintain healthy thyroid hormone levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34054-7
Short code
TSH pre/p TRH SerPl-aCnc
Synonyms
TSH pre/p TRH SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a TSH test to check for thyroid problems, such as hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid). It can also be used to monitor thyroid function during treatment for thyroid disorders or after thyroid surgery.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Avoid smoking, caffeine, or strenuous activity for a few hours before testing.

How the Test Is Performed

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the procedure is quick and usually painless. The blood sample is sent to a lab for analysis.

What the Results Mean

TSH results alone don’t provide a full picture—your doctor will consider them alongside other tests, symptoms, and medical history. Abnormal results may signal thyroid dysfunction, but further evaluation is needed.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: TSH’s Role in Diagnosing Thyroid Disorders

Short name

TSH Level

Frequently asked questions

How often will I need this test?
TSH testing frequency depends on your health status. If you have a known thyroid condition, your doctor may recommend regular monitoring. Otherwise, it’s often done once or twice a year if symptoms arise or during routine check-ups.
What are typical reference ranges for TSH?
Reference ranges vary by lab and may differ slightly between adults and children. A normal TSH level is usually between 0.4–4.0 mIU/L, but your doctor will provide your specific result interpretation based on your health.
Can lifestyle changes affect TSH test results?
Yes, factors like stress, diet (especially iodine intake), and certain medications (e.g., lithium, amiodarone) can influence TSH levels. Your doctor may recommend adjustments to your routine or ask you to avoid these influences before testing.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy