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Serum/plasma thyrotropin (TSH) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH is a hormone produced by your pituitary gland that helps regulate thyroid function.

Quick summary

["TSH helps your thyroid produce hormones that control metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50534-7
Short code
TSH sp2 SerPl-aCnc
Synonyms
TSH sp2 SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a TSH test to check for thyroid problems, such as hypothyroidism (when your thyroid isn’t producing enough hormones) or hyperthyroidism (when it’s overactive). It’s often the first test for thyroid issues because it’s sensitive and easy to perform. TSH levels can also be checked during pregnancy, before surgery, or if you have symptoms like fatigue, weight changes, or unexplained mood swings.

What to Expect Before the Test

No special preparation is usually needed, but your doctor might ask you to fast for a few hours before the blood draw if you’re having it done in the morning. Wear comfortable clothing and plan to rest afterward, as you might feel lightheaded or tired after the needle is inserted.

What Happens During the Test?

A healthcare professional will clean the area on your arm with an antiseptic solution and insert a small needle into a vein. Blood will be gently drawn into a test tube. The process usually takes a few minutes, and you may feel a brief pinch. The blood sample is then sent to a lab for testing.

What Are Possible Results?

Results can vary depending on your health, age, and other factors. Your doctor will compare your TSH level to a reference range specific to your situation and explain what it means for you. High or low TSH levels may signal thyroid dysfunction, which your doctor will discuss with you further.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

TSH Level

Frequently asked questions

What Does a High TSH Level Mean?
A high TSH level often indicates hypothyroidism, meaning your thyroid isn’t working properly and isn’t producing enough hormones. This can lead to symptoms like fatigue, weight gain, cold intolerance, or depression. Your doctor may recommend treatment, such as thyroid hormone medication, to restore balance.
What Does a Low TSH Level Mean?
A low TSH level may suggest hyperthyroidism, where your thyroid is overactive and producing too many hormones. Symptoms can include weight loss, anxiety, rapid heartbeat, or tremors. Your doctor may order additional tests, like free thyroxine (T4) levels, to confirm the diagnosis and guide treatment.
What If My TSH Level Is Within Normal Range?
If your TSH level is normal, it means your thyroid is likely functioning correctly. However, your doctor may still recommend follow-up tests or monitoring if you have symptoms or risk factors for thyroid issues. Always discuss your results with your healthcare provider for personalized advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy