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Thyroid-stimulating hormone (TSH) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood. TSH is a hormone produced by your pituitary gland that helps regulate your thyroid function.

Quick summary

["TSH helps your thyroid produce hormones that control metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50539-6
Short code
TSH sp7 SerPl-aCnc
Synonyms
TSH sp7 SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.4
Ref high
4
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84443
SNOMED
301343003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a TSH test to check for thyroid problems, such as hypothyroidism (when your thyroid isn’t working enough) or hyperthyroidism (when it’s working too much). It’s often the first test done to evaluate thyroid function, especially if you have symptoms like fatigue, weight changes, or unexplained issues with your heart or digestion.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a larger blood panel. Bring any medications you’re taking, as some (like certain thyroid medications) can affect results.

How the Test Works

A small sample of blood is drawn from a vein in your arm. The blood is then sent to a lab, where it’s analyzed to measure TSH levels using an immunoassay method.

What the Results Mean

Results help doctors determine whether your thyroid is functioning normally. Abnormally high or low TSH levels may indicate thyroid disorders that require further testing or treatment.

Reference range

Adult: 0.4-4.0 mIU/LN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

TSH is a key marker for thyroid health. Low TSH often signals hyperthyroidism, while high TSH usually points to hypothyroidism. Since TSH can fluctuate slightly over time, doctors may repeat the test if initial results are borderline or if symptoms persist.

Short name

TSH Level

Frequently asked questions

What causes TSH levels to be checked?
TSH levels are checked if you have symptoms like unexplained weight changes, fatigue, depression, or irregular menstrual periods. It’s also used to monitor thyroid replacement therapy in people with hypothyroidism.
Can diet or medications affect TSH results?
Yes, certain medications (like some antidepressants, steroids, or thyroid medications) can influence TSH levels. Eating a balanced diet rich in iodine may also affect thyroid function, so it’s best to discuss any changes with your doctor.
How long does it take to get TSH results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will review them and discuss any follow-up steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy