Total Antioxidant Capacity of Serum (measured by Trolox Equivalent Antioxidant Capacity)

What Does This Test Measure?

Total antioxidant capacity (TAC) evaluates the combined effect of various antioxidants in your serum, including vitamins (like vitamin C and E), enzymes, and other molecules that neutralize free radicals. Free radicals are unstable molecules that can damage cells and contribute to aging and disease. This test quantifies the serum’s ability to scavenge these harmful particles.

Why Might You Need This Test?

Doctors may order this test to assess oxidative stress in conditions like chronic inflammation, metabolic disorders, or after exposure to oxidative stressors (e.g., smoking, radiation therapy). It can also help monitor treatment responses in certain diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The serum portion (liquid after clotting) is separated and analyzed. This test is usually performed on fresh or stored serum samples, often within a few days of collection.

Common Uses and Clinical Contexts

This test is not routinely ordered for general health screening but may be used in specialized settings, such as evaluating antioxidant status in patients with chronic diseases (e.g., diabetes, cardiovascular disease) or assessing oxidative damage post-treatment.