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Sulfate ion concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sulfate, a mineral derived from sulfur, in your blood plasma or serum. Sulfate plays a role in metabolism and is involved in the production of certain compounds like amino acids and neurotransmitters.

Quick summary

["Understanding your sulfate levels may help assess metabolic health or identify potential deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33673-5
Short code
TT imm SO4 PPP
Synonyms
TT imm SO4 PPP
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-thrombin-factor-induced-factor-substitution-immediately-after-addition-of-protamine-sulfate
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions that could affect sulfate metabolism, such as kidney disease, certain genetic disorders, or unexplained metabolic issues. It may also be part of broader evaluations for conditions like sulfatidosis or other lysosomal storage disorders.

What Does the Result Mean?

Results are not typically provided as a single reference range since sulfate levels can vary based on health status, diet, and other factors. High or low levels may signal underlying health concerns that your doctor will discuss with you.

Common Reasons for Testing

This test is less commonly performed than others but may be included in specialized metabolic screening, particularly in cases suspected of genetic disorders affecting sulfur metabolism.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate plasma or serum, which is then analyzed for sulfate concentration using a specialized laboratory method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum/plasma sulfate

Frequently asked questions

What causes sulfate levels to be tested?
Sulfate levels are primarily tested in specialized clinical settings when there is a suspicion of genetic disorders involving sulfur metabolism, such as sulfatidosis, or when evaluating patients with unexplained metabolic abnormalities.
How is the test performed?
The test involves drawing blood, which is then processed to measure sulfate concentration in plasma or serum using advanced laboratory techniques.
Are there any risks or side effects from this test?
There are generally minimal risks associated with blood drawing, such as mild bruising or discomfort at the injection site. No additional side effects are expected from the sulfate measurement itself.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy