Vaginal and Genital Microbiome Profile (DNA-Based)
This test analyzes the DNA from vaginal and genital swabs to identify and assess the types and balance of microbes present, which can help evaluate health or potential infections.
["Understanding your vaginal and genital microbiome can support reproductive and urinary health."]
Key facts at a glance
- LOINC
- 91844-1
- Short code
- T vaginalis DNA Genital Ql NAA+probe
- Synonyms
- T vaginalis DNA Genital Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms like unusual discharge, itching, odor, or discomfort in the vaginal or genital area. It can also be used for research or monitoring conditions like bacterial vaginosis, sexually transmitted infections (STIs), or other microbial imbalances.
What to Expect During the Test
You’ll collect a sample using a sterile swab from the vaginal or genital region. The sample is then sent to a lab for DNA analysis. No special preparation is needed, but avoid sexual activity or douching 24 hours before the test.
How the Results Are Interpreted
Results show the presence and relative amounts of different microbial DNA. A balanced microbiome typically includes beneficial bacteria like *Lactobacillus*, while harmful bacteria or fungi may indicate an imbalance. Your provider will discuss findings in the context of your symptoms and medical history.
Common Uses and Limitations
This test helps diagnose or monitor infections, track microbial shifts after treatments, or support research. However, it’s not a replacement for traditional culture tests or clinical judgment. Results alone don’t confirm a diagnosis—your provider will interpret them with your full medical picture.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An altered vaginal or genital microbiome can contribute to infections (e.g., yeast infections, bacterial vaginosis), inflammation, or increased risk of STIs. Understanding microbial composition may guide targeted treatments or preventive strategies, though more research is needed to fully standardize clinical use.
Short name
Microbial DNA Profile (Vaginal/Genital Swab)
Frequently asked questions
What does a ‘microbial profile’ mean in this test?
Will I need to fast or avoid certain foods before this test?
Can this test detect sexually transmitted infections (STIs) like chlamydia or gonorrhea?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy