Vaginal and Oral Microbiome Profile via DNA Sequencing (16S rRNA Gene Analysis)
This test analyzes DNA from samples collected from your vagina and mouth to identify the types and amounts of bacteria present. It helps assess the balance of microbes in these areas, which can influence health and potential infections.
["Understanding your body’s natural bacteria balance can help prevent infections and support overall health."]
Key facts at a glance
- LOINC
- 112401-5
- Short code
- T vaginalis DNA Mouth Ql NAA+probe
- Synonyms
- T vaginalis DNA Mouth Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms like unusual vaginal discharge, itching, or mouth sores, or if you’re at higher risk for infections like bacterial vaginosis or oral thrush. It can also be part of routine monitoring for certain conditions or after treatments that affect your microbiome.
How the Test Works
A swab is used to collect samples from your vagina and mouth. The DNA from these bacteria is then extracted and analyzed using genetic sequencing to identify specific bacterial species. This helps determine the diversity and composition of your microbiome.
Sample Collection and Preparation
You’ll likely be asked to collect samples during a visit to your healthcare provider. The swabs are gentle and non-invasive. The lab processes the samples to isolate and analyze bacterial DNA, which takes several days to complete.
What the Results Mean
Results show the presence and relative amounts of different bacteria. A healthy microbiome typically has a balanced mix of beneficial bacteria. Abnormal patterns may indicate an imbalance (dysbiosis) that could contribute to infections or other health issues.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test can help diagnose infections like bacterial vaginosis, oral candidiasis, or other microbiome-related conditions. It may also guide treatment decisions, such as probiotics or targeted antibiotics, by identifying which bacteria are present and their roles in your health. Some conditions may not have symptoms but can still affect well-being.
Short name
Microbiome Test
Frequently asked questions
How long does it take to get my results?
What does it mean if my test shows an imbalance in my vaginal or oral bacteria?
Can I take anything special before my test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy