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Vaginal Microbiome Profile via DNA Probe Analysis

Published: August 9, 2026Updated: August 16, 2026

This test examines the types and balance of bacteria naturally found in your vagina using a DNA probe to assess vaginal health.

Quick summary

["Understanding your vaginal microbiome helps identify imbalances that may cause symptoms or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70165-6
Short code
T vaginalis rRNA Vag Ql NAA+probe
Synonyms
T vaginalis rRNA Vag Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test measures the levels of important hormones and related substances in your body. Hormones act as chemical messengers that help regulate metabolism, energy, mood, sleep, and reproductive health. By measuring these levels, your healthcare provider can determine whether they fall within a normal, healthy range for you.

The test detects specific bacterial DNA sequences present in vaginal fluids. It identifies common bacteria like Lactobacillus (which supports health) and potential pathogens (like *Candida* or *Gardnerella*). The probe method allows for a broad overview of microbial diversity without measuring exact concentrations.

Your provider may order this test if you have symptoms such as unusual fatigue, unexplained weight changes, mood swings, sleep disturbances, irregular periods, or changes in appetite. It can also be used to monitor an existing condition, investigate possible hormonal imbalance, or check how well a current treatment is working.

A vaginal microbiome test may be recommended if you experience recurrent vaginal infections, unusual discharge, itching, or discomfort. It can also help diagnose conditions like bacterial vaginosis or yeast infections by assessing microbial balance.

The sample is usually collected through a simple blood draw. A trained technician will clean the skin on your arm, wrap a band around your upper arm, and collect a small amount of blood from a vein into a sealed tube. The procedure takes only a few minutes, and most people can return to their normal activities right away.

A healthcare provider will collect a sample from your vagina using a sterile swab or probe. The sample is then analyzed in a lab to identify bacterial DNA patterns.

Common findings include hormone levels that fall within the expected range, or results that come back higher or lower than normal. An abnormal result may suggest a hormonal imbalance, thyroid dysfunction, chronic stress, or another underlying condition. Your provider will interpret your results together with your symptoms and medical history before recommending next steps.

Typically, a healthy vaginal microbiome is dominated by *Lactobacillus* species, which help maintain acidity and prevent harmful bacteria. Abnormal findings might include reduced *Lactobacillus* levels or the presence of unusual bacteria, which could indicate an imbalance.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vaginal Microbiome Test

Frequently asked questions

This test helps diagnose and monitor conditions like bacterial vaginosis, yeast infections, or other microbial imbalances that may not be detected by traditional cultures. Early identification can guide targeted treatment and prevent complications such as pelvic inflammatory disease or preterm labor.
Most results are available within a few business days, though some specialized tests may take up to a week or longer. Your healthcare provider's office will typically contact you once the results are ready, and you can also review them through your patient portal if one is available.
Results are usually available within 3–7 business days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
If your results show an imbalance, your provider will explain what it may mean and whether additional testing is needed. Depending on the cause, treatment may involve medication, lifestyle adjustments, or regular follow-up monitoring to help bring your levels back into a healthy range.
If your test shows an imbalance, your doctor may recommend probiotics, antifungal medications, or antibiotics tailored to the specific bacteria identified. Lifestyle changes, such as avoiding douching or certain hygiene products, may also help restore balance.
No, this test is a complementary tool. It may be used alongside other tests (like cultures or pH tests) to provide a fuller picture of your vaginal health. Always follow your healthcare provider’s guidance for interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy