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Total Antioxidant Capacity of Plasma (ORAC-like measurement)

Published: August 9, 2026Updated: August 16, 2026

This test measures the overall ability of your blood plasma to neutralize harmful free radicals, which can help protect cells from oxidative stress.

Quick summary

["Assesses your body’s natural antioxidant defenses in your blood plasma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79926-2
Short code
TV ann s-prime Vmax TDI
Synonyms
TV ann s-prime Vmax TDI
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-tissue-doppler
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test evaluates the combined capacity of various antioxidants in plasma—including vitamins (like vitamin C and E), enzymes, and other molecules—to neutralize free radicals. Free radicals are unstable molecules that can cause cellular damage if left unchecked. This measurement is often expressed as an ORAC (Oxygen Radical Absorbance Capacity) value, which quantifies the total antioxidant power of the sample.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms or conditions linked to oxidative stress, such as chronic inflammation, certain autoimmune diseases, or after exposure to environmental toxins. It may also be used in research or clinical settings to monitor antioxidant status in specific populations.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The plasma portion is separated and analyzed using a specialized method (likely a colorimetric or fluorescence-based assay) to determine its antioxidant capacity. Results are compared to a standard reference range to interpret the findings.

What Do the Results Mean?

Lower than expected results may indicate insufficient antioxidant defenses, potentially contributing to oxidative damage. Higher than expected results could suggest an overabundance of antioxidants, though this is less common. Interpretation depends on clinical context, including your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Plasma Antioxidant Capacity

Frequently asked questions

What factors could affect my results?
Several factors may influence your plasma antioxidant capacity, including diet (e.g., intake of fruits, vegetables, and supplements), lifestyle (e.g., smoking, alcohol use), chronic illnesses, and medications. Recent physical activity, stress, or illness may also temporarily alter results.
How often should I get this test?
This test is not a routine screening and is typically ordered based on specific clinical needs or research purposes. Your doctor will determine the appropriate frequency based on your health status and symptoms.
Can I prepare for this test in any way?
No special preparation is usually required. Avoid heavy meals or excessive alcohol before the test, as they may temporarily alter blood chemistry. Follow your doctor’s instructions if you have any concerns.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy