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Tyrosine concentration in urine (24-hour collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of tyrosine, an amino acid, excreted in your urine over a 24-hour period. It may be used to assess metabolic or genetic conditions affecting amino acid metabolism.

Quick summary

["This test helps evaluate how well your body processes certain amino acids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33021-7
Short code
Tyrosine Cry #/area UrnS LPF
Synonyms
Tyrosine Cry #/area UrnS LPF
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-lpf
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a family history suggestive of metabolic disorders, such as tyrosinemia or other aminoacidopathies. It could also be part of a broader evaluation for unexplained health concerns related to amino acid metabolism.

What to Expect Before the Test

You’ll need to collect all urine produced in a 24-hour period, typically starting after midnight one day and ending the same time the next day. Wear a urine collection container and keep it refrigerated. Follow your provider’s instructions carefully to ensure accurate results.

How the Test Is Performed

Urine samples are sent to a lab for analysis. The test measures tyrosine concentration using a specialized method, often involving chromatography or immunoassay, to detect and quantify the amino acid in your urine.

What the Results Mean

Results may be compared to a reference range specific to your age, sex, and health status. Elevated levels might indicate metabolic disorders, while lower levels could suggest other conditions or errors in collection. Your provider will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal tyrosine levels in urine can signal underlying metabolic disorders, such as tyrosinemia or other aminoacidopathies. These conditions may cause symptoms like fatigue, developmental delays, or organ damage. Early detection and management are crucial for preventing complications.

Short name

24-Hour Urine Tyrosine

Frequently asked questions

What causes abnormal tyrosine levels in urine?
Abnormal tyrosine levels can result from genetic metabolic disorders that impair amino acid breakdown, dietary factors (e.g., excessive tyrosine intake), or errors in urine collection. Always discuss any concerns with your healthcare provider.
How can I prepare for this test?
No special diet or fasting is required, but follow your provider’s instructions precisely for accurate urine collection. Avoid certain medications or supplements that might interfere with results if directed by your provider.
Is this test painful or uncomfortable?
No, this test involves only urine collection and does not require needles or injections. The process is simple and typically done at home with guidance from your healthcare team.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy