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Serum Immunoassay for Anti-Smooth Muscle Antibodies (ASMA)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures antibodies that may indicate an autoimmune condition affecting the liver and other organs.

Quick summary

["ASMA antibodies can help diagnose conditions like autoimmune hepatitis or other liver-related disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110083-3
Short code
U1 snRNP70 Ab Msmt Ser
Synonyms
U1 snRNP70 Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is an ASMA Antibody Test Used For?

ASMA antibodies are part of a panel often used to identify autoimmune diseases that target liver cells. They may also be checked if you have symptoms like unexplained liver issues, fatigue, or jaundice. This test helps doctors determine whether your symptoms could be linked to an autoimmune response.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab for testing using an immunoassay method to detect the presence of ASMA antibodies.

What Are Common Symptoms That Might Lead to This Test?

ASMA antibodies are often checked in people with symptoms like persistent fatigue, abdominal pain, jaundice (yellowing of skin/eyes), unexplained weight loss, or liver enzyme abnormalities detected on other tests. They may also be part of a broader evaluation for autoimmune conditions.

How Does This Test Fit Into My Healthcare Plan?

Your doctor may order this test if they suspect an autoimmune liver disease, such as autoimmune hepatitis, or if you have other signs of liver dysfunction. It’s often used alongside other tests, like liver function tests, to guide treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ASMA Antibody Test

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may recommend this test if you have symptoms like unexplained liver issues, fatigue, or signs of an autoimmune condition. It’s also sometimes used as part of a screening or monitoring plan for people at higher risk of autoimmune liver diseases.
What does a positive result mean?
A positive result suggests the presence of ASMA antibodies, which may indicate an autoimmune liver condition. However, this alone doesn’t confirm a diagnosis. Your doctor will review the results alongside other tests and symptoms to make a full assessment.
How often will I need this test?
The frequency depends on your health status and treatment plan. If you’re diagnosed with an autoimmune liver disease, your doctor may recommend regular monitoring to track disease activity or response to treatment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy