Serum Immunoassay for Anti-Smooth Muscle Antibodies (ASMA) (Qualitative)
This test checks for antibodies that may indicate an autoimmune condition affecting the liver or other organs, such as autoimmune hepatitis or other connective tissue diseases.
["Helps diagnose certain autoimmune liver diseases by detecting specific antibodies in your blood."]
Key facts at a glance
- LOINC
- 63316-4
- Short code
- U1 snRNP70 Ab Ser IA-aCnc
- Synonyms
- U1 snRNP70 Ab Ser IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, jaundice (yellowing of skin/eyes), liver pain, or if they suspect an autoimmune condition affecting your liver or other organs. It’s also used to monitor certain conditions like autoimmune hepatitis or scleroderma.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your lab requires it. Bring any medications you’re currently taking, as some may affect results.
What the Test Involves
A blood sample will be drawn from a vein in your arm by a healthcare professional. The process is quick and typically causes mild discomfort. The serum portion of your blood is then tested for specific antibodies using an immunoassay method.
What the Results Mean
Positive results suggest the presence of ASMA antibodies, which may signal an autoimmune liver disease or other conditions like scleroderma. Negative results mean no detectable antibodies were found in this test. Results should always be interpreted by your provider in the context of your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: ASMA Antibodies and Autoimmune Conditions
Short name
ASMA Antibody Test (Serum)
Frequently asked questions
What does a positive ASMA antibody test indicate?
Can ASMA antibodies be found in other conditions besides autoimmune diseases?
How often should I get this test if I have a history of autoimmune conditions?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy