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Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and plays a key role in long-term immunity.

Quick summary

["IgG helps fight infections and supports long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63367-7
Short code
U1 snRNP Ab Titr Ser IA
Synonyms
U1 snRNP Ab Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is the most common type of antibody in your blood. It’s produced by your immune system in response to infections and vaccines. This test helps doctors assess your immune response, check for immune deficiencies, or monitor conditions like certain autoimmune diseases or chronic infections.

Why Might You Need This Test?

Doctors may order this test if you have symptoms of low immunity (like frequent infections), if you’ve had a recent infection or vaccination, or if you’re being treated for conditions like lupus, HIV, or certain cancers. It can also help monitor immune responses in newborns or people with immune disorders.

How Is the Test Done?

A blood sample is taken from a vein in your arm. The blood is sent to a lab where it’s processed to separate serum (the liquid part without blood cells). The lab then measures the IgG concentration using an immunoassay method, which detects the antibody’s presence.

What Are Possible Results?

Results are typically reported as a concentration value (e.g., grams per liter). While reference ranges vary by lab, lower than expected levels may suggest immune deficiency, and higher levels could indicate chronic infections, inflammation, or certain immune disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding IgG Levels

Short name

IgG Level

Frequently asked questions

Could my IgG levels be affected by medications I’m taking?
Yes, some medications—like steroids, chemotherapy drugs, or certain antibiotics—can lower IgG levels. If you’re on long-term treatment, your doctor may monitor your IgG as part of your care plan.
What if my IgG level is too low?
Low IgG can make you more prone to infections. Your doctor may recommend additional tests (like checking for immune deficiencies) or suggest treatments like immunoglobulin therapy if needed.
How often should I get this test?
Your doctor will decide based on your health needs. Some people get it once, while others (like those with immune disorders) may need it regularly to track changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy