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Serum or Plasma Protein Electrophoresis with Bromocresol Green (BCG) Dye Binding Assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood, including albumin and globulins, using a dye-binding method to assess protein fractions.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like liver disease, kidney problems, or multiple myeloma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110081-7
Short code
U1 snRNP IgG Msmt Ser
Synonyms
U1 snRNP IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test separates blood proteins into different fractions—such as albumin, alpha, beta, and gamma globulins—using an electric charge and a dye (bromocresol green). Each protein group absorbs the dye differently, allowing for their relative quantification.

Why Might You Need This Test?

Your doctor may order this test to diagnose or monitor conditions affecting protein levels, such as liver disease (e.g., cirrhosis), kidney disease, or certain cancers like multiple myeloma.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The sample is processed to separate serum or plasma, then analyzed using the BCG dye-binding method to measure protein fractions.

Common Conditions Monitored

This test helps detect shifts in protein balance that can indicate conditions like hypoalbuminemia (low albumin), elevated globulins (e.g., in chronic inflammation or autoimmune diseases), or abnormal protein spikes (e.g., monoclonal gammopathy).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis (BCG)

Frequently asked questions

What does a 'protein electrophoresis' tell me about my health?
It provides a detailed breakdown of your blood proteins, helping identify whether certain protein groups are too high or too low, which can point to conditions like liver disease, kidney problems, or cancers.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your doctor will determine if additional testing or actions are needed.
Can I eat or drink before this test?
No special diet is required, but avoid alcohol for 24 hours before the test, as it may affect protein levels. Follow your doctor’s instructions for any fasting requirements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy