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Uric Acid, Serum or Plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of uric acid, a waste product from the breakdown of certain foods and substances in your body, found in your blood.

Quick summary

["Uric acid levels help assess kidney function and risk for conditions like gout."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2196-4
Short code
u DHEA SerPl-mCnc
Synonyms
u DHEA SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82626
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Uric Acid Does in Your Body

Uric acid is produced when your body breaks down purines, which are found in certain foods (like organ meats, shellfish, and red meat) and naturally occur in your body. It circulates in your bloodstream and is filtered out by your kidneys to be excreted in urine. High levels can indicate problems with kidney function or may contribute to conditions like gout, where urate crystals form in joints.

Why It’s Tested

Doctors may order this test to evaluate kidney health, diagnose gout, or monitor treatment for conditions affecting uric acid metabolism. It can also help identify underlying metabolic disorders.

Common Reasons for Testing

Common reasons include suspected kidney disease, unexplained joint pain (possible gout), or when other blood tests suggest abnormal purine metabolism. Some people may also have it checked as part of routine health screenings or before certain treatments.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves a blood draw. Avoid consuming alcohol or high-purine foods for 24 hours beforehand if instructed by your provider.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Uric Acid

Frequently asked questions

What does a high uric acid level mean?
High uric acid levels can signal kidney issues, where the body isn’t filtering waste properly, or may indicate conditions like gout, where urate crystals form painful deposits in joints. Elevated levels can also be linked to other health concerns like hypertension or obesity.
What does a low uric acid level mean?
Low uric acid levels are less common but may suggest certain genetic disorders affecting purine metabolism or kidney problems that prevent normal excretion. Your doctor will consider other factors, like diet or medications, when interpreting results.
Does diet affect uric acid test results?
Yes, diet can influence uric acid levels. High-purine foods (like organ meats, certain seafood, and processed foods) may temporarily raise levels, while hydration and a balanced diet can help maintain normal levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy