Estrogen (conjugated, urinary 24-hour collection)
This test measures the total amount of conjugated estrogens—water-soluble forms of estrogen—excreted in your urine over 24 hours. It helps assess estrogen levels in the body, particularly useful for monitoring hormone therapy or detecting conditions affecting estrogen metabolism.
["This test helps track estrogen balance and supports diagnosis of hormonal conditions."]
Key facts at a glance
- LOINC
- 2260-8
- Short code
- u Estrone Amn-mCnc
- Synonyms
- u Estrone Amn-mCnc
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions related to estrogen levels, such as irregular menstrual cycles, hormone-related cancers, or to evaluate the effectiveness of hormone replacement therapy. It may also be used during pregnancy or to monitor certain reproductive health conditions.
What to Expect Before the Test
You will need to collect a 24-hour urine sample starting from midnight one day and ending midnight the next. Collect all urine in a refrigerator or on ice. Do not miss any urine, including the first and last samples. Follow your provider’s specific instructions for preparation, such as avoiding certain medications or foods.
What Happens During the Test
No special preparation is required at the lab, but the urine sample must be processed and analyzed by a specialized method. The test involves measuring the total conjugated estrogens in your urine, which is then compared to standard reference ranges.
What the Results Mean
Results are interpreted based on your clinical context and symptoms. Elevated levels may indicate conditions like estrogen-producing tumors or certain liver issues, while lower levels might suggest hormonal imbalances or deficiencies. Your provider will discuss these findings with you.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Urinary conjugated estrogens
Frequently asked questions
What are the typical reference ranges for this test?
How often should I get this test?
Can I take certain medications before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy