UDP-glucuronosyltransferase 1A9 gene variant analysis (qualitative)
This test checks for specific genetic variations in the UGT1A9 gene, which may affect how your body processes certain medications or metabolic processes.
Your genetic makeup can influence how drugs and your body’s chemistry work together.
Key facts at a glance
- LOINC
- 104299-3
- Short code
- UGT1A9 gene.1b-118(dT)9>10 Bld/T Ql
- Synonyms
- UGT1A9 gene.1b-118(dT)9>10 Bld/T Ql
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
UGT1A9 is an enzyme involved in the metabolism of drugs and toxins. Variations in this gene can alter how efficiently your liver processes medications like certain antibiotics, pain relievers, or chemotherapy drugs. This test identifies whether you carry certain genetic changes in the UGT1A9 gene that might impact drug metabolism.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have a history of unusual drug reactions, liver issues, or if you’re taking medications known to rely on UGT1A9 for metabolism. It can also be part of genetic testing for conditions related to metabolic enzyme function.
Common Uses and Considerations
This test is primarily used to assess genetic predispositions that could influence drug response. It’s not typically used for routine screening but may be part of a broader genetic evaluation for personalized medicine or specific health concerns.
What to Expect Before the Test
No special preparation is needed for this genetic test. A small blood sample is usually collected, similar to other blood tests. If testing involves saliva or another specimen, your provider will guide you on preparation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Variations in the UGT1A9 gene can lead to altered drug metabolism, potentially causing either reduced effectiveness of medications or increased risk of side effects. For example, certain genetic variants may make you more or less likely to experience adverse reactions to medications metabolized by this enzyme. This information can help your healthcare team tailor treatment plans to your genetic profile.
Short name
UGT1A9 Gene Test
Frequently asked questions
Will this test show if I’m taking too many medications?
How long will it take to get results?
Can this test be done if I’m pregnant?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy