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UDP-glucuronosyltransferase 1A9 gene sequencing (qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic variations in the UGT1A9 gene, which may affect how your body processes certain medications or metabolic pathways.

Quick summary

["Knowing your UGT1A9 genetic makeup can help doctors tailor treatment plans for better safety and effectiveness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104302-5
Short code
UGT1A9 gene.c.-275T>A Bld/T Ql
Synonyms
UGT1A9 gene.c.-275T>A Bld/T Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you’re considering medications that rely on UGT1A9 activity, such as certain antibiotics, pain relievers, or anti-inflammatory drugs. It can also be part of broader genetic screening for metabolic or drug response evaluations.

What the Test Measures

The test analyzes specific DNA sequences in the UGT1A9 gene to identify common genetic variants. These variants can influence how efficiently your liver metabolizes drugs or other substances.

Sample Collection and Process

A blood sample is typically collected to extract DNA for analysis. The lab processes the DNA to detect any known UGT1A9 gene variations without providing specific numeric results.

Common Uses in Medicine

UGT1A9 gene sequencing helps personalize medication dosing, especially for drugs metabolized by this enzyme. It may also be used in research or rare genetic conditions linked to metabolic dysfunctions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Variations in the UGT1A9 gene can alter drug metabolism rates, potentially leading to either reduced effectiveness of certain medications or increased risk of side effects. This information supports safer, more targeted treatment strategies.

Short name

UGT1A9 Gene Test

Frequently asked questions

What does a positive or negative result mean?
A positive result indicates the presence of known UGT1A9 gene variants. These variants may influence how your body processes specific medications, but they don’t always predict drug response without clinical context.
Will this test affect my medication choices?
Possibly. If your results show relevant variants, your doctor may adjust your medication regimen to optimize safety or effectiveness, but this depends on the specific drug and clinical context.
How long does it take to get results?
Results are typically available within 1–2 weeks, depending on the lab’s processing time and follow-up requirements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy