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UGT1A9 Gene Mutation Status (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks whether you carry a specific genetic variation in the UGT1A9 gene, which may influence how your body processes certain medications.

Quick summary

["A genetic test to help determine how your body may handle specific medications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104300-9
Short code
UGT1A9 gene.p.M33T Bld/T Ql
Synonyms
UGT1A9 gene.p.M33T Bld/T Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re considering medications that are metabolized by the UGT1A9 enzyme, such as certain pain relievers, antidepressants, or blood pressure medications. It helps assess potential drug interactions or side effects.

What to Expect Before the Test

No special preparation is needed. You’ll likely provide a blood sample, similar to other routine blood tests. Your provider will explain the process and answer any questions.

What the Results Mean

Results will indicate whether you have the UGT1A9 genetic variation. This information can guide your doctor in selecting the safest medication dose or alternative treatments.

Common Medications Affected

UGT1A9 influences metabolism of drugs like acetaminophen (Tylenol), some antidepressants, and certain painkillers. Variations may affect how quickly your body breaks down these medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Genetic Testing for Drug Response

Short name

UGT1A9 Gene Test

Frequently asked questions

What does a positive or negative result mean for my health?
A positive result means you carry the UGT1A9 genetic variant. While this doesn’t directly impact your health, it may influence how your body processes certain medications, potentially affecting their effectiveness or safety. Discuss this with your provider to tailor your treatment plan.
Could this test affect my prescription choices?
Yes, if you’re on medications metabolized by UGT1A9, your doctor may adjust your dose or suggest alternatives to minimize risks. Genetic testing helps personalize treatment for better safety and outcomes.
Is this test covered by insurance?
Coverage depends on your insurance plan and clinical indication. Check with your provider or insurance company to confirm if this test is approved for your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy