Uric Acid, Serum/Plasma (Concentration)

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like joint pain (especially in the big toe), frequent kidney infections, or if you’re at risk for conditions like gout, kidney stones, or certain types of arthritis. It may also be checked during routine health evaluations or if you’re taking medications that affect uric acid levels, such as certain diuretics or low-dose aspirin.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Drink plenty of water the day before to help your kidneys process uric acid normally. Avoid excessive alcohol or high-purine foods (like organ meats, shellfish, or red meat) 24 hours before testing, as they can temporarily raise uric acid levels.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis. The test typically takes a few minutes, and you can resume normal activities immediately afterward.

What the Results Mean

Results are compared to a general reference range, but individual ranges can vary by lab. High uric acid levels may indicate kidney problems, gout, or other metabolic conditions, while very low levels might suggest certain genetic disorders or liver/kidney disease. Your provider will discuss your specific results in the context of your overall health.