Skip to content

Serum or plasma substance concentration (electrochemiluminescence immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific protein or substance in your blood, typically using a sensitive immunoassay method. It helps detect or monitor conditions related to that substance’s levels.

Quick summary

["This test assesses your blood levels of a particular marker, often used for diagnosis or tracking treatment progress."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60617-8
Short code
UIE-A FH Skull XR
Synonyms
UIE-A FH Skull XR
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence and concentration of a specific substance (e.g., a hormone, enzyme, or antibody) in your blood. The method used may involve detecting chemical reactions that produce measurable signals, such as light or electrical currents, to quantify the substance accurately.

Why It’s Ordered

Your healthcare provider may order this test to diagnose or monitor conditions like infections, autoimmune diseases, hormonal imbalances, or other metabolic disorders. It can also help assess how well a treatment is working or detect early signs of potential health issues.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum (liquid part after clotting) or plasma (liquid part after centrifugation), which is sent to the lab for testing. The test may require fasting or specific timing instructions, depending on the analyte.

Common Uses in Healthcare

This test is often used in screening, diagnosing, or managing conditions such as thyroid disorders, kidney function, inflammation, or genetic disorders. It may also be part of routine check-ups or follow-up care for chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

None

Frequently asked questions

How does this test differ from other blood tests I’ve had before?
Unlike general blood panels (e.g., CBC or chemistry panels), this test focuses on a single or very specific substance. It’s often more sensitive and tailored to detect subtle changes in that particular marker, which can be critical for conditions where small fluctuations matter (e.g., certain hormones or proteins).
What do abnormal results mean?
Abnormal results can indicate underlying health issues, such as excess or deficiency of the measured substance. For example, high levels might suggest inflammation, infection, or a tumor, while low levels could point to nutritional deficiencies, organ dysfunction, or genetic disorders. Your provider will interpret results in the context of your symptoms and medical history.
Can I prepare for this test differently than other blood tests?
Yes, some tests may require fasting (e.g., 8–12 hours before), avoiding certain medications, or limiting specific foods/drinks. Always follow your provider’s instructions. If you’re unsure, ask your lab technician or healthcare team about any special preparations.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy