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Cerebrospinal Fluid (CSF) Cell Count (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks the number of cells in your cerebrospinal fluid (CSF), which is the fluid surrounding your brain and spinal cord. It helps identify whether there are abnormal cells present, such as those seen in infections, inflammation, or other neurological conditions.

Quick summary

["A CSF cell count helps diagnose conditions affecting your nervous system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13527-7
Short code
Unident Cells NFr CSF Manual
Synonyms
Unident Cells NFr CSF Manual
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like headaches, neck stiffness, confusion, or neurological problems. It’s often used to investigate conditions such as meningitis, multiple sclerosis, or other brain/spinal cord issues.

What to Expect Before the Test

You’ll likely have a lumbar puncture (spinal tap) to collect the CSF. This involves lying on your side and having a needle inserted into your lower back. The procedure is usually quick but may cause mild discomfort. You may be asked to empty your bladder beforehand.

What the Test Results Mean

The test is qualitative, meaning it provides a general count of cells rather than specific numbers. High cell counts may indicate inflammation, infection, or blood in the CSF. Low counts could suggest a lack of abnormal cells but don’t rule out all conditions.

Common Conditions Monitored

This test is critical in diagnosing or ruling out conditions like bacterial meningitis, viral meningitis, multiple sclerosis, brain tumors, or other neurological disorders that affect CSF composition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CSF Cell Count (Qualitative)

Frequently asked questions

What does a high or low cell count mean?
A high cell count (elevated white blood cells) often signals an infection, inflammation, or blood leakage into the CSF. A low cell count may suggest normal CSF or conditions like Guillain-Barré syndrome, but further testing is needed to confirm.
How long does it take to get results?
Results are typically available within hours to a few days, depending on lab processing. Your provider will discuss findings with you during follow-up.
Can I eat or drink before this test?
You may drink water but avoid solid foods for a few hours before the procedure. Follow your provider’s specific instructions for hydration and rest.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy