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Serum or plasma uric acid concentration (substance concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of uric acid in your blood, a natural breakdown product of purines (chemicals found in foods and body cells). High levels may indicate conditions like gout or kidney issues.

Quick summary

["Uric acid levels help diagnose or monitor potential health problems related to metabolism or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73945-8
Short code
UR-144 Bld Ql
Synonyms
UR-144 Bld Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like joint pain (especially in big toes), kidney problems, or if you’re at risk for gout or kidney stones. It’s also used to monitor treatments for conditions affecting uric acid levels.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your test is part of a broader metabolic panel. Bring any medications you’re taking to your appointment.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The sample is sent to a lab for analysis, where uric acid levels are measured using an immunoassay or enzymatic method.

What the Results Mean

Results are compared to a reference range specific to your age, sex, and overall health. High levels may signal metabolic disorders or kidney dysfunction, while very low levels could indicate certain genetic conditions or liver/kidney problems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Uric Acid

Frequently asked questions

What does uric acid measure?
Uric acid measures the concentration of this substance in your blood, which can reflect how well your body is processing waste products from purines. Elevated levels may raise concerns about gout, kidney disease, or other metabolic disorders.
How is this test different from a urine uric acid test?
This test specifically measures uric acid in serum or plasma (blood), while a urine uric acid test evaluates how much uric acid is excreted in urine over time (e.g., 24-hour collection). Both can be used together for a fuller picture.
Can diet affect uric acid levels?
Yes, diet can influence uric acid levels. High-purine foods (e.g., red meat, organ meats, certain seafood) may increase levels, while hydration and certain medications (like allopurinol) can help manage them. Always discuss dietary changes with your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy