Urate [Mass concentration] in 24 hour Urine

What This Test Measures

Urate, commonly called uric acid, is a waste product made when your body breaks down purines, substances found in your cells and in certain foods. Your kidneys filter urate out of the blood and send it into urine. This test measures the mass (weight-based amount) of urate collected in all the urine you produce over one full day, giving a clearer picture than a single spot urine sample.

How the 24-Hour Collection Works

You will be given a large collection container and instructions. Typically, you discard the first urine you pass at the start of the collection period, then save every drop of urine for the next 24 hours, including the first sample passed at the end of the period. The container is usually kept cool and returned to the lab. Following the timing and storage instructions carefully is important because an incomplete collection can make results unreliable.

What the Results Can Mean

Results are interpreted alongside your symptoms, diet, medications, and blood tests. A high urine urate level can suggest the body is producing or excreting a lot of uric acid, which may raise the risk of uric acid kidney stones or reflect certain metabolic patterns. A low level may point to factors such as kidney handling of urate, diet, or medications. Your clinician will explain what your specific value means for you.

Preparation and Things to Tell Your Care Team

Tell your healthcare provider about all medications and supplements you take, because some can affect urate levels. Ask whether you should change your diet or fluid intake during the collection. Avoid losing any urine during the 24 hours and note the exact start and stop times. Report any spills, missed samples, or collection problems so the lab and your provider can interpret the result correctly.