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Urate (Uric Acid) and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 17, 2026

Measures urate and creatinine in urine collected for 24 hours. The results help assess uric acid excretion and account for differences in urine concentration.

Quick summary

["This test can help evaluate how much uric acid your body is excreating, especially when kidney function or uric acid handling needs assessment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
75642-9
Short code
Urate/Creat 24h Ur-sRto
Synonyms
Urate/Creat 24h Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures uric acid, also called urate, and creatinine in all urine collected over a 24-hour period. Creatinine is used to help account for variation in urine concentration, so the two results may be interpreted together.

Why might I need this test?

A clinician may order it to evaluate uric acid excretion, investigate high or low urate levels, or assess uric acid handling when evaluating gout, kidney function, or treatment with uric acid-lowering medication.

How is the test performed?

You collect all urine into a special container for exactly 24 hours. The laboratory then measures the amount of urate and creatinine in the collected sample, and the results may be compared to determine the relative amount of urate being excreted.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory, including the exact start and stop times. Continue normal daily activities and fluid intake unless your clinician gives different instructions, and return the container promptly as directed.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urate result may occur with increased purine breakdown, reduced kidney excretion, certain medications, or dietary influences. A low result may occur in some nutritional, metabolic, liver, or kidney-related conditions. The 24-hour collection and creatinine measurement help provide context, but results should be interpreted by a clinician along with symptoms, medications, and other laboratory tests.

Short name

24-hour urine urate and creatinine

Frequently asked questions

What is the difference between urate and uric acid?
Urate is the form of uric acid commonly measured in blood and urine. In laboratory reports, urate and uric acid are often used to describe the same measurement.
Why is creatinine included in this urine test?
Urine concentration can vary from person to person and throughout the day. Creatinine provides a way to compare urate excretion with urine output and other factors.
What happens if part of the urine collection is missed?
A missed collection can make the 24-hour result inaccurate and may require the test to be repeated. Follow the laboratory's timing and storage instructions carefully.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy